Bachelor of Science [B.Sc] (Biochemistry)

Biochem course is aimed to provide academic research and skills for a successful career in Biochemistry. The course delivery methods consist of lectures, practical lab work and workshops. In the final assessment, tutorials, end-semester examination and projects are taken into consideration.

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Syllabus

Though the syllabus may vary from college to college, the topics are more or less similar. The syllabus is based on Core Courses. The detailed syllabus is as follows:-

Name of Course

Topics

Description

Biomolecules

Biomolecules

Carbohydrate

Lipids

Amino acids

Nucleic acids

Vitamins

A Biomolecule is a molecule which is involved in the maintenance and metabolic processes of living organisms.

Biophysics

Origin and Evolution of Life

Biophysics of Water

Electrochemistry

Photophysics

Spectroscopic Techniques

Hydrodynamic Techniques

Optical Techniques

Diffraction Techniques

Radioactivity and measurement

Biophysics introduces a student to application of the laws of Physics to biological phenomena.

Chemistry

Atomic Structure

Chemical Bonding and Molecular Structure

Chemical Thermodynamics

Ionic Equilibrium

Fundamentals of Organic Chemistry

Stereochemistry

Carbohydrates

Amino Acids, Peptides and Proteins

This is a basic course on chemistry

Biochemical Techniques

Separation Techniques

Chromatography

Electrophoresis

Centrifugation

Spectrophotometry

Flourimetry

This paper introduces to the biochemical techniques used for understanding biochemical processes.

Mathematics & Statistics

Calculus

Sequences and Multivariate Calculus

Statistic

This is a basic course on the study of Mathematics and Statistics

Proteins and Enzymes

Proteins and Enzymes

Hierarchy of protein structure

Primary structure analysis

Secondary structure

Tertiary and Quartenary structure

Introduction to enzymes,

Features of enzyme catalysis

Enzyme kinetics

Mechanism of action of selected enzymes

Coenzymes and their mechanisms-

Regulation of enzyme activity

Irreversible inhibitors

This course introduces to the structure, functions and reactions of Proteins and Enzymes.

Metabolism of Carbohydrates & Lipids

Introduction to Intermediary metabolism

Glucose: central role in metabolism

TCA cycle

Other pathways of carbohydrate metabolism

Carbohydrate synthesis

Glycogen metabolism

Lipid digestion

Fatty acids Oxidation

Ketone Bodies

Biosynthesis of lipids

Arachidonate metabolism

Starve Feed Cycle

Cholesterol metabolism in animals

Through this course students study about Metabolism of Carbohydrates & Lipids

Cell Biology

An Overview of Cells

Tools and techniques of Cell Biology

Composition of Cells

The Nucleus

Protein Sorting and Transport

 Mitochondria, Chloroplasts and Peroxisomes

Cytoskeleton and Cell Movement

The Plasma Membrane

Cell Wall, the Extracellular Matrix and Cell Interactions

Cell Signaling

 The Cell Cycle

Cell Death and Cell Renewal

Cancer

Cells are the basic structural, functional and biological unit of life. This course deals with an in-depth study of cells.

Molecular Biology

Nucleic Acids convey Genetic Information

The Structures of DNA and RNA / Genetic Material

 Genome Structure, Chromatin and the Nucleosome

The Replication of DNA (Prokaryotes and Eukaryotes)

The Mutability and Repair of DNA

Mechanism of Transcription

RNA Modifications

Translation (Prokaryotes and Eukaryotes)

Transcription Regulation in Prokaryotes

Transcription Regulation in Eukaryotes

Regulatory RNAs

This is a course about molecular biology and its use in biochemistry

Bioenergetics

Principles of chemical thermodynamics

Biological oxidation and reduction

Mitochondria and Oxidative phosphorylation

Photophosphorylation

Bioluminescence

This course focuses on the study of the transformation of energy in living organisms.

Metabolism of Amino acids & Nucleotides

Nitrogen Cycle

Nitrogen Balance

Outlines of Amino Acids metabolism

Degradation of the carbon skeleton

Biosynthesis of Amino Acids

Disorders of amino acid metabolism

Precursor function of Amino acids

Biosynthesis of urine nucleotides

Biosynthesis of pyrimidine nucleotides

Deoxy ribonucleotides and synthesis of DTTP

Degradation of purine and pyrimidine nucleotides.

Disorders of nucleotide metabolism

In this course students will study the principles of Metabolism of Amino acids & Nucleotides

Membrane Biology

Introduction

Composition of Biomembranes

Model Membrane Systems

Membrane Structures

 Asymmetry in Membranes

Membrane Dynamics

Membrane transport

This is a course on the study about biology and structure of membrane.

Hormone Biochemistry

Introduction

Cell signalling & Mechanism of Hormone action

Intra-cellular Receptors

Hormones

Hypothalamic Hormones

Pituitary Hormones

Endocrine disorders

Hormones regulating Ca2+ Homeostasis

Pancreatic Hormones

GI tract Hormones

Hormones of Adrenal Cortex

Reproductive Hormones

Other organs with endocrine function

This course studies hormones and various glands in detail.

Immunology

Introduction

Cells and organs of the immune system

Innate immunity

Adaptive immunity

Techniques based on antigen- antibody interactions

Hypersensitivity

Autoimmunity

Immunodeficiency

Immune response against major classes of pathogens

Transplantation immunology

Tumour immunology

Immunomodulation

This studies the branch of biology which is concerned about immunity.

Genetics & Genomics

Introduction to Genetics

Mitosis and Meiosis

 Mendelian Genetics and its Extension

Linkage, Crossing Over and Chromosomal Mapping

Mutations

Sex Determination

 Extrachromosomal Inheritance

Quantitative Genetics

Genetic Analysis and Mapping in Bacteria and Bacteriophages

Genome Dynamics-Transposable genetic elements, Eukaryotic Viruses

Developmental Genetics and Model System

Genomics, Bioinformatics and Proteomics

Genomic Analysis- Dissection of Gene Function

Population Genetics

Evolutionary Genetics

This course deals with the study of genetics and the structure, function and evolution of genomes.

Molecular Physiology

The body fluid compartments

The cardio vascular system

Renal physiology

Respiration

Gastrointestinal and hepatic physiology

Musculosketetal system

Reproductive physiology

Neurophysiology

This course focuses on scientific study of the normal functions of molecules.

Recombinant DNA Technology

Concept and emergence of r-DNA technology

Nucleic acid blotting

Selection and screening of recombinant clones

Expression of cloned DNA

DNA transactions in Microorganisms

Characterization of cloned DNA

Modification of cloned DNA

Comparative genomics

Human Genome Project

Applications of recombinant DNA technology

Recombinant DNA Technology is a series of procedure used to join together DNA fragments.

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